4ZUD

Crystal Structure of Human Angiotensin Receptor in Complex with Inverse Agonist Olmesartan at 2.8A resolution.

Summary for 4ZUD

Entry DOI	10.2210/pdb4zud/pdb
Descriptor	Chimera protein of Soluble cytochrome b562 and Type-1 angiotensin II receptor, Olmesartan (2 entities in total)
Functional Keywords	human angiotensin receptor at1r, bril, g protein-coupled receptor, gpcr, gpcr network, lipidic cubic phase, lcp, membrane protein, structural genomics, olmesartan, angiotensin receptor blocker, anti-hypertensive drug, psi-biology, signaling protein
Biological source	Escherichia coli More
Total number of polymer chains	1
Total formula weight	47168.54
Authors	Zhang, H.,Unal, H.,Desnoyer, R.,Han, G.W.,Patel, N.,Katritch, V.,Karnik, S.S.,Cherezov, V.,Stevens, R.C.,GPCR Network (GPCR) (deposition date: 2015-05-15, release date: 2015-10-07, Last modification date: 2023-09-27)
Primary citation	Zhang, H.,Unal, H.,Desnoyer, R.,Han, G.W.,Patel, N.,Katritch, V.,Karnik, S.S.,Cherezov, V.,Stevens, R.C. Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor. J.Biol.Chem., 290:29127-29139, 2015 Cited by PubMed: 26420482 DOI: 10.1074/jbc.M115.689000 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation