4ZS2
Structural complex of FTO/fluorescein
Summary for 4ZS2
Entry DOI | 10.2210/pdb4zs2/pdb |
Related | 4ZS3 |
Descriptor | Alpha-ketoglutarate-dependent dioxygenase FTO, 2-OXOGLUTARIC ACID, 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, ... (5 entities in total) |
Functional Keywords | inhibitor, fluorescein, fluorescent protein-inhibitor complex, fluorescent protein/inhibitor |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus : Q9C0B1 |
Total number of polymer chains | 1 |
Total formula weight | 55467.31 |
Authors | Wang, T.,Hong, T.,Huang, Y.,Yang, C.G.,Zhou, X. (deposition date: 2015-05-13, release date: 2015-11-04, Last modification date: 2015-11-18) |
Primary citation | Wang, T.,Hong, T.,Huang, Y.,Su, H.,Wu, F.,Chen, Y.,Wei, L.,Huang, W.,Hua, X.,Xia, Y.,Xu, J.,Gan, J.,Yuan, B.,Feng, Y.,Zhang, X.,Yang, C.G.,Zhou, X. Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein J.Am.Chem.Soc., 137:13736-13739, 2015 Cited by PubMed: 26457839DOI: 10.1021/jacs.5b06690 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.16 Å) |
Structure validation
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