4ZRY

Crystal structure of the heterocomplex between coil 2B domains of human intermediate filament proteins keratin 1 (KRT1) and keratin 10 (KRT10)

4ZRY の概要

• エントリーDOI: 10.2210/pdb4zry/pdb
• 分子名称: Keratin, type I cytoskeletal 10, Keratin, type II cytoskeletal 1 (2 entities in total)
• 機能のキーワード: keratin, intermediate filament, coiled-coil, skin, protein-protein complex, epidermis, helix, protein fibril
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Cell membrane : P04264
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 28254.32

構造登録者

Bunick, C.G.,Steitz, T.A. (登録日: 2015-05-12, 公開日: 2016-05-18, 最終更新日: 2023-09-27)

• 主引用文献: Bunick, C.G.,Milstone, L.M.; The X-Ray Crystal Structure of the Keratin 1-Keratin 10 Helix 2B Heterodimer Reveals Molecular Surface Properties and Biochemical Insights into Human Skin Disease.; J. Invest. Dermatol., 137:142-150, 2017; PubMed: 27595935; DOI: 10.1016/j.jid.2016.08.018

実験手法

X-RAY DIFFRACTION (3.30012502044 Å)