4ZRK

Merlin-FERM and Lats1 complex

Summary for 4ZRK

• Entry DOI: 10.2210/pdb4zrk/pdb
• Related: 4ZRI 4ZRJ
• Descriptor: Merlin, Serine/threonine-protein kinase LATS1 (3 entities in total)
• Functional Keywords: merlin, ferm, lats1, signaling protein-transferase complex, signaling protein/transferase
• Biological source: Mus musculus (Mouse); More
• Cellular location: Cell membrane ; Peripheral membrane protein ; Cytoplasmic side : P46662; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome : O95835
• Total number of polymer chains: 8
• Total formula weight: 166595.44

Authors

Lin, Z.,Li, Y.,Wei, Z.,Zhang, M. (deposition date: 2015-05-12, release date: 2015-06-17, Last modification date: 2023-11-08)

• Primary citation: Li, Y.,Zhou, H.,Li, F.,Chan, S.W.,Lin, Z.,Wei, Z.,Yang, Z.,Guo, F.,Lim, C.J.,Xing, W.,Shen, Y.,Hong, W.,Long, J.,Zhang, M.; Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway; Cell Res., 25:801-817, 2015; PubMed: 26045165; DOI: 10.1038/cr.2015.69

Experimental method

X-RAY DIFFRACTION (2.316 Å)