4ZRA

CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS LPRG BINDING TO TRIACYLGLYCERIDE

Summary for 4ZRA

• Entry DOI: 10.2210/pdb4zra/pdb
• Related: 3MH8 3MHA
• Descriptor: Lipoprotein LprG, Tripalmitoylglycerol (3 entities in total)
• Functional Keywords: lprg, lipoprotein, structural genomics, tb structural genomics consortium, tbsgc, lipid binding protein
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• Cellular location: Cell membrane ; Lipid-anchor : P9WK45
• Total number of polymer chains: 2
• Total formula weight: 43737.20

Authors

Martinot, A.J.,Farrow, M.,Bai, L.,Layre, E.,Cheng, T.Y.,Tsai, J.H.C.,Iqbal, J.,Annand, J.,Sullivan, Z.,Hussain, M.,Sacchettini, J.,Moody, D.B.,Seeliger, J.,Rubin, E.J.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2015-05-12, release date: 2016-02-10, Last modification date: 2024-03-06)

• Primary citation: Martinot, A.J.,Farrow, M.,Bai, L.,Layre, E.,Cheng, T.Y.,Tsai, J.H.,Iqbal, J.,Annand, J.W.,Sullivan, Z.A.,Hussain, M.M.,Sacchettini, J.,Moody, D.B.,Seeliger, J.C.,Rubin, E.J.; Mycobacterial Metabolic Syndrome: LprG and Rv1410 Regulate Triacylglyceride Levels, Growth Rate and Virulence in Mycobacterium tuberculosis.; Plos Pathog., 12:e1005351-e1005351, 2016; PubMed: 26751071; DOI: 10.1371/journal.ppat.1005351

Experimental method

X-RAY DIFFRACTION (1.83 Å)