4ZN5
YopH W354Y Yersinia enterocolitica PTPase bond with Divanadate glycerol ester in the active site
Summary for 4ZN5
Entry DOI | 10.2210/pdb4zn5/pdb |
Related | 4YAA |
Descriptor | Tyrosine-protein phosphatase YopH, Divanadate Glycerol ester, VANADATE ION, ... (6 entities in total) |
Functional Keywords | inhibitor, phosphatase, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Yersinia enterocolitica |
Total number of polymer chains | 1 |
Total formula weight | 34072.91 |
Authors | Moise, G.E.,Johnson, S.J.,Hengge, A.C. (deposition date: 2015-05-04, release date: 2015-10-28, Last modification date: 2023-09-27) |
Primary citation | Moise, G.,Gallup, N.M.,Alexandrova, A.N.,Hengge, A.C.,Johnson, S.J. Conservative Tryptophan Mutants of the Protein Tyrosine Phosphatase YopH Exhibit Impaired WPD-Loop Function and Crystallize with Divanadate Esters in Their Active Sites. Biochemistry, 54:6490-6500, 2015 Cited by PubMed: 26445170DOI: 10.1021/acs.biochem.5b00496 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.12 Å) |
Structure validation
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