4ZN5

YopH W354Y Yersinia enterocolitica PTPase bond with Divanadate glycerol ester in the active site

4ZN5 の概要

• エントリーDOI: 10.2210/pdb4zn5/pdb
• 関連するPDBエントリー: 4YAA
• 分子名称: Tyrosine-protein phosphatase YopH, Divanadate Glycerol ester, VANADATE ION, ... (6 entities in total)
• 機能のキーワード: inhibitor, phosphatase, hydrolase-inhibitor complex, hydrolase/inhibitor
• 由来する生物種: Yersinia enterocolitica
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34072.91

構造登録者

Moise, G.E.,Johnson, S.J.,Hengge, A.C. (登録日: 2015-05-04, 公開日: 2015-10-28, 最終更新日: 2023-09-27)

• 主引用文献: Moise, G.,Gallup, N.M.,Alexandrova, A.N.,Hengge, A.C.,Johnson, S.J.; Conservative Tryptophan Mutants of the Protein Tyrosine Phosphatase YopH Exhibit Impaired WPD-Loop Function and Crystallize with Divanadate Esters in Their Active Sites.; Biochemistry, 54:6490-6500, 2015; PubMed: 26445170; DOI: 10.1021/acs.biochem.5b00496

実験手法

X-RAY DIFFRACTION (1.12 Å)