4ZJB

Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase(FabZ) in complex with holo-ACP from Helicobacter pylori

Summary for 4ZJB

Entry DOI	10.2210/pdb4zjb/pdb
Descriptor	3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, Acyl carrier protein, CITRIC ACID, ... (5 entities in total)
Functional Keywords	fas, fatty acid biosynthesis, complex, lyase-biosynthetic protein complex, lyase/biosynthetic protein
Biological source	Helicobacter pylori More
Total number of polymer chains	3
Total formula weight	49137.31
Authors	Zhang, L.,Zhang, L.,Shen, X.,Jiang, H. (deposition date: 2015-04-29, release date: 2016-11-02, Last modification date: 2023-11-08)
Primary citation	Zhang, L.,Xiao, J.,Xu, J.,Fu, T.,Cao, Z.,Zhu, L.,Chen, H.Z.,Shen, X.,Jiang, H.,Zhang, L. Crystal structure of FabZ-ACP complex reveals a dynamic seesaw-like catalytic mechanism of dehydratase in fatty acid biosynthesis. Cell Res., 26:1330-1344, 2016 Cited by PubMed: 27874013 DOI: 10.1038/cr.2016.136 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.55 Å)

Structure validation