4ZJB

Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase(FabZ) in complex with holo-ACP from Helicobacter pylori

4ZJB の概要

• エントリーDOI: 10.2210/pdb4zjb/pdb
• 分子名称: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, Acyl carrier protein, CITRIC ACID, ... (5 entities in total)
• 機能のキーワード: fas, fatty acid biosynthesis, complex, lyase-biosynthetic protein complex, lyase/biosynthetic protein
• 由来する生物種: Helicobacter pylori; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 49137.31

構造登録者

Zhang, L.,Zhang, L.,Shen, X.,Jiang, H. (登録日: 2015-04-29, 公開日: 2016-11-02, 最終更新日: 2023-11-08)

• 主引用文献: Zhang, L.,Xiao, J.,Xu, J.,Fu, T.,Cao, Z.,Zhu, L.,Chen, H.Z.,Shen, X.,Jiang, H.,Zhang, L.; Crystal structure of FabZ-ACP complex reveals a dynamic seesaw-like catalytic mechanism of dehydratase in fatty acid biosynthesis.; Cell Res., 26:1330-1344, 2016; PubMed: 27874013; DOI: 10.1038/cr.2016.136

実験手法

X-RAY DIFFRACTION (2.55 Å)