4ZIL

Crystal structure of Rv2466c and oxidoreductase from Mycobacterium tuberculosis in its reduced state

Summary for 4ZIL

• Entry DOI: 10.2210/pdb4zil/pdb
• Related: 4NXI
• Descriptor: DSBA oxidoreductase, MAGNESIUM ION (3 entities in total)
• Functional Keywords: oxidoreductase
• Biological source: Mycobacterium tuberculosis (H37Rv)
• Cellular location: Cytoplasm : O53193
• Total number of polymer chains: 2
• Total formula weight: 49203.78

Authors

Albesa-Jove, D.,Urresti, S.,Comino, N.,Tersa, M.,Guerin, M.E. (deposition date: 2015-04-28, release date: 2015-11-18, Last modification date: 2024-01-10)

• Primary citation: Albesa-Jove, D.,Comino, N.,Tersa, M.,Mohorko, E.,Urresti, S.,Dainese, E.,Chiarelli, L.R.,Pasca, M.R.,Manganelli, R.,Makarov, V.,Riccardi, G.,Svergun, D.I.,Glockshuber, R.,Guerin, M.E.; The Redox State Regulates the Conformation of Rv2466c to Activate the Antitubercular Prodrug TP053.; J.Biol.Chem., 290:31077-31089, 2015; PubMed: 26546681; DOI: 10.1074/jbc.M115.677039

Experimental method

X-RAY DIFFRACTION (1.507 Å)