4ZGI

Structure of Truncated Human TIFA

Summary for 4ZGI

• Entry DOI: 10.2210/pdb4zgi/pdb
• Related: 4YM4
• Descriptor: TRAF-interacting protein with FHA domain-containing protein A (2 entities in total)
• Functional Keywords: fha domian, adaptor, signaling protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 16720.40

Authors

Weng, J.H.,Wei, T.Y.W.,Hsieh, Y.C.,Huang, C.C.F.,Wu, P.Y.G.,Chen, E.S.W.,Huang, K.F.,Chen, C.J.,Tsai, M.D. (deposition date: 2015-04-23, release date: 2015-10-14, Last modification date: 2015-10-28)

• Primary citation: Weng, J.H.,Hsieh, Y.C.,Huang, C.C.,Wei, T.Y.,Lim, L.H.,Chen, Y.H.,Ho, M.R.,Wang, I.,Huang, K.F.,Chen, C.J.,Tsai, M.D.; Uncovering the Mechanism of Forkhead-Associated Domain-Mediated TIFA Oligomerization That Plays a Central Role in Immune Responses.; Biochemistry, 54:6219-6229, 2015; PubMed: 26389808; DOI: 10.1021/acs.biochem.5b00500

Experimental method

X-RAY DIFFRACTION (2.701 Å)