4ZEL

Human dopamine beta-hydroxylase

4ZEL の概要

• エントリーDOI: 10.2210/pdb4zel/pdb
• 分子名称: Dopamine beta-hydroxylase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: hydroxylase, dimer, copper binding, oxidoreductase
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Soluble dopamine beta-hydroxylase: Cytoplasmic vesicle, secretory vesicle lumen. Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type II membrane protein: P09172
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 132883.70

構造登録者

Vendelboe, T.V.,Harris, P.,Christensen, H.E.M.,Harlos, K.,Walter, T.,Zhao, Y.,Omari, K. (登録日: 2015-04-20, 公開日: 2016-04-20, 最終更新日: 2020-07-29)

• 主引用文献: Vendelboe, T.V.,Harris, P.,Zhao, Y.,Walter, T.S.,Harlos, K.,El Omari, K.,Christensen, H.E.; The crystal structure of human dopamine beta-hydroxylase at 2.9 angstrom resolution.; Sci Adv, 2:e1500980-e1500980, 2016; PubMed: 27152332; DOI: 10.1126/sciadv.1500980

実験手法

X-RAY DIFFRACTION (2.9 Å)