4ZAO

Genetically engineered Carbonic anhydrase IX

Summary for 4ZAO

• Entry DOI: 10.2210/pdb4zao/pdb
• Related: 4YMP
• Descriptor: Carbonic anhydrase 2, ZINC ION (3 entities in total)
• Functional Keywords: ca ix mimic, lyase
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm : P00918
• Total number of polymer chains: 1
• Total formula weight: 29266.30

Authors

Pinard, M.A.,Aggarwal, M. (deposition date: 2015-04-13, release date: 2015-10-14, Last modification date: 2024-03-06)

• Primary citation: Pinard, M.A.,Aggarwal, M.,Mahon, B.P.,Tu, C.,McKenna, R.; A sucrose-binding site provides a lead towards an isoform-specific inhibitor of the cancer-associated enzyme carbonic anhydrase IX.; Acta Crystallogr F Struct Biol Commun, 71:1352-1358, 2015; PubMed: 26457530; DOI: 10.1107/S2053230X1501239X

Experimental method

X-RAY DIFFRACTION (1.8 Å)