4Z9O

Crystal Structure of human GGT1

Summary for 4Z9O

Entry DOI	10.2210/pdb4z9o/pdb
Descriptor	Gamma-glutamyltranspeptidase 1, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (7 entities in total)
Functional Keywords	ntn-hydrolase family, glycoprotein, n- glycosylation, cell surface, hydrolase, transferase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	60359.72
Authors	Terzyan, S.S.,Hanigan, M.H. (deposition date: 2015-04-10, release date: 2015-06-03, Last modification date: 2020-07-29)
Primary citation	Terzyan, S.S.,Burgett, A.W.,Heroux, A.,Smith, C.A.,Mooers, B.H.,Hanigan, M.H. Human gamma-Glutamyl Transpeptidase 1: STRUCTURES OF THE FREE ENZYME, INHIBITOR-BOUND TETRAHEDRAL TRANSITION STATES, AND GLUTAMATE-BOUND ENZYME REVEAL NOVEL MOVEMENT WITHIN THE ACTIVE SITE DURING CATALYSIS. J.Biol.Chem., 290:17576-17586, 2015 Cited by PubMed: 26013825 DOI: 10.1074/jbc.M115.659680 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation