4Z90
ELIC bound with the anesthetic isoflurane in the resting state
Summary for 4Z90
Entry DOI | 10.2210/pdb4z90/pdb |
Related | 3RQU 3RQW |
Descriptor | Gamma-aminobutyric-acid receptor subunit beta-1, (2R)-2-chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (4 entities in total) |
Functional Keywords | elic, isoflurane, inhibition, anesthetics, resting state, transport protein |
Biological source | Dickeya dadantii (strain 3937) |
Total number of polymer chains | 10 |
Total formula weight | 371480.34 |
Authors | |
Primary citation | Chen, Q.,Kinde, M.N.,Arjunan, P.,Wells, M.M.,Cohen, A.E.,Xu, Y.,Tang, P. Direct Pore Binding as a Mechanism for Isoflurane Inhibition of the Pentameric Ligand-gated Ion Channel ELIC. Sci Rep, 5:13833-13833, 2015 Cited by PubMed: 26346220DOI: 10.1038/srep13833 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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