4Z77

Weak TCR binding to an unstable insulin epitope drives type 1 diabetes

Summary for 4Z77

• Entry DOI: 10.2210/pdb4z77/pdb
• Descriptor: H-2 class I histocompatibility antigen, K-D alpha chain, Beta-2-microglobulin, Insulin, ... (8 entities in total)
• Functional Keywords: immunoglobulin, h-2kd, type 1 diabetes, immune system
• Biological source: Mus musculus (House Mouse); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01902; Secreted : P61769 P01308
• Total number of polymer chains: 6
• Total formula weight: 97124.62

Authors

Rizkallah, P.J.,Cole, D.K. (deposition date: 2015-04-06, release date: 2015-06-24)

• Primary citation: Rizkallah, P.J.,Cole, D.K.; Weak TCR binding to an unstable insulin epitope drives type 1 diabetes; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.85 Å)