4Z4C

Human Argonaute2 Bound to t1-C Target RNA

Summary for 4Z4C

• Entry DOI: 10.2210/pdb4z4c/pdb
• Related: 4Z4D 4Z4E 4Z4F 4Z4G 4Z4I
• Descriptor: Protein argonaute-2, RNA (5'-R(P*UP*UP*CP*AP*CP*AP*UP*UP*GP*CP*CP*CP*AP*AP*GP*UP*CP*UP*U)-3'), RNA (5'-R(*CP*AP*AP*UP*GP*UP*GP*AP*C)-3'), ... (8 entities in total)
• Functional Keywords: argonaute2, mirna, hydrolase-rna complex, hydrolase/rna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 108139.63

Authors

Schirle, N.T.,MacRae, I.J. (deposition date: 2015-04-02, release date: 2015-09-23, Last modification date: 2024-03-06)

• Primary citation: Schirle, N.T.,Sheu-Gruttadauria, J.,Chandradoss, S.D.,Joo, C.,MacRae, I.J.; Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.; Elife, 4:-, 2015; PubMed: 26359634; DOI: 10.7554/eLife.07646

Experimental method

X-RAY DIFFRACTION (2.303 Å)