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4Z2W

Factor Inhibiting HIF in Complex with Fe, and Alpha-Ketoglutarate

Summary for 4Z2W
Entry DOI10.2210/pdb4z2w/pdb
Related4Z1V
DescriptorHypoxia-inducible factor 1-alpha inhibitor, 2-OXOGLUTARIC ACID, DI(HYDROXYETHYL)ETHER, ... (6 entities in total)
Functional Keywordshypoxia inducible factor, factor inhibiting hif, oxygenase, oxygen sensing, oxidoreductase
Biological sourceHomo sapiens (Human)
Cellular locationNucleus: Q9NWT6
Total number of polymer chains1
Total formula weight41398.93
Authors
Taabazuing, C.Y.,Garman, S.C.,Knapp, M.J. (deposition date: 2015-03-30, release date: 2016-01-13, Last modification date: 2024-03-06)
Primary citationTaabazuing, C.Y.,Fermann, J.,Garman, S.,Knapp, M.J.
Substrate Promotes Productive Gas Binding in the alpha-Ketoglutarate-Dependent Oxygenase FIH.
Biochemistry, 55:277-286, 2016
Cited by
PubMed: 26727884
DOI: 10.1021/acs.biochem.5b01003
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

217705

數據於2024-03-27公開中

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