4Z1B
Structure of H204A mutant KDO8PS from H.pylori
Summary for 4Z1B
| Entry DOI | 10.2210/pdb4z1b/pdb |
| Related | 4Z1A 4Z1C 4Z1D |
| Descriptor | 2-dehydro-3-deoxyphosphooctonate aldolase (2 entities in total) |
| Functional Keywords | helicobacter pylori, lipopolysaccharide biosynthesis, mutant, transferase |
| Biological source | Helicobacter pylori (strain ATCC 700392 / 26695) |
| Cellular location | Cytoplasm : P56060 |
| Total number of polymer chains | 2 |
| Total formula weight | 60629.70 |
| Authors | Lee, B.J.,Cho, S.,Im, H.,Yoon, H.J. (deposition date: 2015-03-27, release date: 2016-03-09, Last modification date: 2024-03-20) |
| Primary citation | Cho, S.,Im, H.,Lee, K.Y.,Chen, J.,Kang, H.J.,Yoon, H.J.,Min, K.H.,Lee, K.R.,Park, H.J.,Lee, B.J. Identification of novel scaffolds for potential anti-Helicobacter pylori agents based on the crystal structure of H. pylori 3-deoxy-d-manno-octulosonate 8-phosphate synthase (HpKDO8PS). Eur.J.Med.Chem., 108:188-202, 2016 Cited by PubMed: 26649906DOI: 10.1016/j.ejmech.2015.11.036 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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