4YVY

Crystal structure of human carbonic anhydrase II in complex with hydroxylamine-O-sulfonamide, a molecule incorporating two zinc-binding groups.

Summary for 4YVY

• Entry DOI: 10.2210/pdb4yvy/pdb
• Related: 1CA2
• Descriptor: Carbonic anhydrase 2, ZINC ION, amino(aminooxy)sulfane dioxide, ... (4 entities in total)
• Functional Keywords: protein-inhibitor complex, lyase
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm : P00918
• Total number of polymer chains: 1
• Total formula weight: 29335.38

Authors

Di Fiore, A.,De Simone, G. (deposition date: 2015-03-20, release date: 2016-03-30)

• Primary citation: Di Fiore, A.,Vergara, A.,Caterino, M.,Alterio, V.,Monti, S.M.,Ombouma, J.,Dumy, P.,Vullo, D.,Supurand, C.T.,Winum, J.-Y.,De Simone, G.; A VERSATILE ZINC-BINDING GROUP FOR CARBONIC ANHYDRASE INHIBITORS; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.45 Å)