4YTM

Crystal structure of Mitochondrial rhodoquinol-fumarate reductase from Ascaris suum with N-biphenyl-3-yl-2-(trifluoromethyl)benzamide

Summary for 4YTM

• Entry DOI: 10.2210/pdb4ytm/pdb
• Related: 4YSX 4YSY 4YSZ 4YT0 4YTN 4YTP 4YXD
• Descriptor: Succinate dehydrogenase flavoprotein, PROTOPORPHYRIN IX CONTAINING FE, N-biphenyl-3-yl-2-(trifluoromethyl)benzamide, ... (12 entities in total)
• Functional Keywords: oxidoreductase, rhodoquinol-fumarate reductase, complex ii, inhibitor, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Ascaris suum (Pig roundworm); More
• Total number of polymer chains: 8
• Total formula weight: 288545.75

Authors

Harada, S.,Shiba, T.,Sato, D.,Yamamoto, A.,Nagahama, M.,Yone, A.,Inaoka, D.K.,Sakamoto, K.,Inoue, M.,Honma, T.,Kita, K. (deposition date: 2015-03-18, release date: 2015-08-05, Last modification date: 2023-11-08)

• Primary citation: Inaoka, D.K.,Shiba, T.,Sato, D.,Balogun, E.O.,Sasaki, T.,Nagahama, M.,Oda, M.,Matsuoka, S.,Ohmori, J.,Honma, T.,Inoue, M.,Kita, K.,Harada, S.; Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria; Int J Mol Sci, 16:15287-15308, 2015; PubMed: 26198225; DOI: 10.3390/ijms160715287

Experimental method

X-RAY DIFFRACTION (3.4 Å)