4YQI

Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds

Summary for 4YQI

• Entry DOI: 10.2210/pdb4yqi/pdb
• Descriptor: tRNA (guanine-N(1)-)-methyltransferase, (4-amino-1,2,5-oxadiazol-3-yl)[4-(pyridin-2-ylmethyl)piperazin-1-yl]methanone (3 entities in total)
• Functional Keywords: trmd, sam-binding, knot, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
• Cellular location: Cytoplasm : P43912
• Total number of polymer chains: 1
• Total formula weight: 28672.88

Authors

Elkins, P.A.,Bonnette, W.G.,Madauss, K.P.,Stuckey, J.A. (deposition date: 2015-03-13, release date: 2016-03-16, Last modification date: 2023-09-27)

• Primary citation: Elkins, P.A.,Bonnette, W.G.,Williams, S.P.,Stuckey, J.A.; Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.92 Å)