4YON

P-Rex1:Rac1 complex

Summary for 4YON

• Entry DOI: 10.2210/pdb4yon/pdb
• Descriptor: Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein, Ras-related C3 botulinum toxin substrate 1 (3 entities in total)
• Functional Keywords: protein binding
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 65538.19

Authors

Lucato, C.M.,Whisstock, J.C.,Ellisdon, A.M. (deposition date: 2015-03-11, release date: 2015-07-01, Last modification date: 2023-09-27)

• Primary citation: Lucato, C.M.,Halls, M.L.,Ooms, L.M.,Liu, H.J.,Mitchell, C.A.,Whisstock, J.C.,Ellisdon, A.M.; The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer Cells.; J.Biol.Chem., 290:20827-20840, 2015; PubMed: 26112412; DOI: 10.1074/jbc.M115.660456

Experimental method

X-RAY DIFFRACTION (1.95 Å)