4YON

P-Rex1:Rac1 complex

4YON の概要

• エントリーDOI: 10.2210/pdb4yon/pdb
• 分子名称: Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein, Ras-related C3 botulinum toxin substrate 1 (3 entities in total)
• 機能のキーワード: protein binding
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 65538.19

構造登録者

Lucato, C.M.,Whisstock, J.C.,Ellisdon, A.M. (登録日: 2015-03-11, 公開日: 2015-07-01, 最終更新日: 2023-09-27)

• 主引用文献: Lucato, C.M.,Halls, M.L.,Ooms, L.M.,Liu, H.J.,Mitchell, C.A.,Whisstock, J.C.,Ellisdon, A.M.; The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer Cells.; J.Biol.Chem., 290:20827-20840, 2015; PubMed: 26112412; DOI: 10.1074/jbc.M115.660456

実験手法

X-RAY DIFFRACTION (1.95 Å)