4YO2

Structure of E2F8, an atypical member of E2F family of transcription factors

Summary for 4YO2

• Entry DOI: 10.2210/pdb4yo2/pdb
• Descriptor: Transcription factor E2F8, DNA (5'-D(P*TP*TP*TP*TP*CP*CP*CP*GP*CP*CP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*GP*GP*CP*GP*GP*GP*AP*AP*AP*A)-3') (3 entities in total)
• Functional Keywords: transcription factor, e2f family, dna-complex, transcription, fusion protein
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : A0AVK6
• Total number of polymer chains: 3
• Total formula weight: 36080.12

Authors

Morgunova, E.,Yin, Y.,Jolma, A.,Dave, K.,Schmierer, B.,Popov, A.,Eremina, N.,Nilsson, L.,Taipale, J. (deposition date: 2015-03-11, release date: 2015-12-09, Last modification date: 2024-01-10)

• Primary citation: Morgunova, E.,Yin, Y.,Jolma, A.,Dave, K.,Schmierer, B.,Popov, A.,Eremina, N.,Nilsson, L.,Taipale, J.; Structural insights into the DNA-binding specificity of E2F family transcription factors.; Nat Commun, 6:10050-10050, 2015; PubMed: 26632596; DOI: 10.1038/ncomms10050

Experimental method

X-RAY DIFFRACTION (3.073 Å)