4YNR

DosS GAFA Domain Reduced CO Bound Crystal Structure

Summary for 4YNR

Entry DOI	10.2210/pdb4ynr/pdb
Related	2W3D 2W3F
Descriptor	Redox sensor histidine kinase response regulator DevS, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE, ... (4 entities in total)
Functional Keywords	doss, tuberculosis, heme, gas sensor, oxidoreductase
Biological source	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Total number of polymer chains	2
Total formula weight	34975.13
Authors	Madrona, Y. (deposition date: 2015-03-10, release date: 2016-02-24, Last modification date: 2024-02-28)
Primary citation	Basudhar, D.,Madrona, Y.,Kandel, S.,Lampe, J.N.,Nishida, C.R.,de Montellano, P.R. Analysis of cytochrome P450 CYP119 ligand-dependent conformational dynamics by two-dimensional NMR and X-ray crystallography. J.Biol.Chem., 290:10000-10017, 2015 Cited by PubMed: 25670859 DOI: 10.1074/jbc.M114.627935 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.92 Å)

Structure validation