4YNC

OYE1 W116A COMPLEXED WITH (Z)-METHYL-3-CYANO-3-PHENYLACRYLATE IN A NON PRODUCTIVE BINDING MODE

4YNC の概要

• エントリーDOI: 10.2210/pdb4ync/pdb
• 関連するPDBエントリー: 4GBU
• 分子名称: NADPH dehydrogenase 1, FLAVIN MONONUCLEOTIDE, methyl (2Z)-3-cyano-3-phenylprop-2-enoate, ... (5 entities in total)
• 機能のキーワード: oxidoreductase, catalytic activity, fmn binding, old yellow enzyme
• 由来する生物種: Saccharomyces pastorianus (Lager yeast)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 45245.94

構造登録者

Santangelo, S.,Brenna, E.,Stewart, J.D.,Powell III, R.W. (登録日: 2015-03-09, 公開日: 2016-01-20, 最終更新日: 2024-01-10)

• 主引用文献: Brenna, E.,Crotti, M.,Gatti, F.G.,Monti, D.,Parmeggiani, F.,Powell III, R.W.,Santangelo, S.,Stewart, J.D.; Opposite Enantioselectivity in the Bioreduction of (Z)-beta-Aryl-beta-cyanoacrylates Mediated by the Tryptophan 116 Mutants of Old Yellow Enzyme 1: Synthetic Approach to (R)- and (S)-beta-Aryl-gamma-lactams; Adv.Synth.Catal., 357:1849-1860., 2015; DOI: 10.1002/adsc.201500206

実験手法

X-RAY DIFFRACTION (1.498 Å)