4YIH

Crystal structure of human cytosolic 5'(3')-deoxyribonucleotidase in complex with the inhibitor PB-PVU

4YIH の概要

• エントリーDOI: 10.2210/pdb4yih/pdb
• 分子名称: 5'(3')-deoxyribonucleotidase, cytosolic type, MAGNESIUM ION, PHOSPHATE ION, ... (6 entities in total)
• 機能のキーワード: 5'-nucleotidase, dephosphorylation, phosphorylation, had-like, mitochondria, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 46945.58

構造登録者

Pachl, P.,Rezacova, P.,Brynda, J. (登録日: 2015-03-02, 公開日: 2015-09-09, 最終更新日: 2024-01-10)

• 主引用文献: Pachl, P.,Simak, O.,Rezacova, P.,Fabry, M.,Budesinsky, M.,Rosenberg, I.,Brynda, J.; Structure-based design of a bisphosphonate 5'(3')-deoxyribonucleotidase inhibitor; Medchemcomm, 6:1635-1638, 2015; DOI: 10.1039/C5MD00235D

実験手法

X-RAY DIFFRACTION (1.82 Å)