4YI5

Crystal structure of Gpb in complex with 4b

Summary for 4YI5

Entry DOI	10.2210/pdb4yi5/pdb
Related	4YI3
Descriptor	Glycogen phosphorylase, muscle form, PYRIDOXAL-5'-PHOSPHATE, N-({(2E)-3-[4-(propan-2-yl)phenyl]prop-2-enoyl}carbamoyl)-beta-D-glucopyranosylamine, ... (5 entities in total)
Functional Keywords	alpha and beta protein, transferase
Biological source	Oryctolagus cuniculus (Rabbit)
Total number of polymer chains	1
Total formula weight	98412.17
Authors	Kantsadi, A.L.,Chatzileontiadou, D.S.M.,Stravodimos, G.A.,Leonidas, D.D. (deposition date: 2015-02-27, release date: 2015-11-18, Last modification date: 2024-01-10)
Primary citation	Kantsadi, A.L.,Parmenopoulou, V.,Bakalov, D.N.,Snelgrove, L.,Stravodimos, G.A.,Chatzileontiadou, D.S.,Manta, S.,Panagiotopoulou, A.,Hayes, J.M.,Komiotis, D.,Leonidas, D.D. Glycogen phosphorylase as a target for type 2 diabetes: synthetic, biochemical, structural and computational evaluation of novel N-acyl-N -( beta-D-glucopyranosyl) urea inhibitors. Curr Top Med Chem, 15:2373-2389, 2015 Cited by PubMed: 26088352 DOI: 10.2174/1568026615666150619142253 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation