4YGA

CDPK1, from Toxoplasma gondii, bound to inhibitory VHH-1B7

Summary for 4YGA

Entry DOI	10.2210/pdb4yga/pdb
Descriptor	Calmodulin-domain protein kinase 1, VHH-1B7, CALCIUM ION (3 entities in total)
Functional Keywords	serine/threonine protein kinase, vhh domain, inhibitor, metal binding protein
Biological source	Toxoplasma gondii More
Total number of polymer chains	8
Total formula weight	296551.59
Authors	Knockenhauer, K.E.,Schwartz, T.U. (deposition date: 2015-02-26, release date: 2015-08-26, Last modification date: 2017-09-20)
Primary citation	Ingram, J.R.,Knockenhauer, K.E.,Markus, B.M.,Mandelbaum, J.,Ramek, A.,Shan, Y.,Shaw, D.E.,Schwartz, T.U.,Ploegh, H.L.,Lourido, S. Allosteric activation of apicomplexan calcium-dependent protein kinases. Proc.Natl.Acad.Sci.USA, 112:E4975-E4984, 2015 Cited by PubMed: 26305940 DOI: 10.1073/pnas.1505914112 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.94 Å)

Structure validation