4YCW

Crystal structure of cladosporin in complex with plasmodium like human lysyl-tRNA synthetase mutant

Summary for 4YCW

• Entry DOI: 10.2210/pdb4ycw/pdb
• Related: 4YCU 4YCV
• Descriptor: Lysine--tRNA ligase, Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, LYSINE, ... (5 entities in total)
• Functional Keywords: inhibitor, complex, lysrs, cladosporin, ligase-ligase inhibitor complex, ligase/ligase inhibitor
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 258209.22

Authors

Fang, P.,Wang, J.,Guo, M. (deposition date: 2015-02-20, release date: 2015-06-10, Last modification date: 2023-09-27)

• Primary citation: Fang, P.,Han, H.,Wang, J.,Chen, K.,Chen, X.,Guo, M.; Structural Basis for Specific Inhibition of tRNA Synthetase by ATP Competitive Inhibitor; Chem.Biol., 22:1-, 2015

Experimental method

X-RAY DIFFRACTION (2.9 Å)