4YBL
Crystal structure of the stabilized inner domain of clade A/E HIV-1 gp120 in complex with the ADCC mediating ANTI-HIV-1 antibody A32
Summary for 4YBL
Entry DOI | 10.2210/pdb4ybl/pdb |
Related | 3TNM 4H8W 4RQH 4YC2 |
Descriptor | Stabilized inner domain of clade A/E gp120, A32 antibody Fab heavy chain, A32 antibody light chain (3 entities in total) |
Functional Keywords | adcc, non-neutralizing, anti-hiv-1 env antibody a32, cd4i antibody, viral glycoprotein gp120, hiv-1 env, viral protein-immune system complex, viral protein/immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 6 |
Total formula weight | 126843.38 |
Authors | Tolbert, W.D.,Gohain, N.,Pazgier, M. (deposition date: 2015-02-18, release date: 2016-03-02, Last modification date: 2023-09-27) |
Primary citation | Tolbert, W.D.,Gohain, N.,Veillette, M.,Chapleau, J.P.,Orlandi, C.,Visciano, M.L.,Ebadi, M.,DeVico, A.L.,Fouts, T.R.,Finzi, A.,Lewis, G.K.,Pazgier, M. Paring Down HIV Env: Design and Crystal Structure of a Stabilized Inner Domain of HIV-1 gp120 Displaying a Major ADCC Target of the A32 Region. Structure, 24:697-709, 2016 Cited by PubMed: 27041594DOI: 10.1016/j.str.2016.03.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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