4Y60
Structure of SOX18-HMG/PROX1-DNA
Summary for 4Y60
Entry DOI | 10.2210/pdb4y60/pdb |
Descriptor | Transcription factor SOX-18, DNA (5'-D(*CP*AP*CP*TP*AP*GP*CP*AP*TP*TP*GP*TP*CP*TP*GP*GP*G)-3'), DNA (5'-D(*GP*CP*CP*CP*AP*GP*AP*CP*AP*AP*TP*GP*CP*TP*AP*GP*T)-3'), ... (4 entities in total) |
Functional Keywords | transcription factor, sox, protein-dna, transcription-dna complex, transcription/dna |
Biological source | Mus musculus (Mouse) More |
Cellular location | Nucleus: P43680 |
Total number of polymer chains | 3 |
Total formula weight | 20186.19 |
Authors | Narasimhan, K.,Prokoph, N.,Kolatkar, P.,Robinson, H.,Jauch, R. (deposition date: 2015-02-12, release date: 2016-03-02, Last modification date: 2024-03-20) |
Primary citation | Klaus, M.,Prokoph, N.,Girbig, M.,Wang, X.,Huang, Y.H.,Srivastava, Y.,Hou, L.,Narasimhan, K.,Kolatkar, P.R.,Francois, M.,Jauch, R. Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA interaction. Nucleic Acids Res., 44:3922-3935, 2016 Cited by PubMed: 26939885DOI: 10.1093/nar/gkw130 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
Download full validation report