4Y1X

Complex of human Galectin-1 and Galbeta1-4(6OSO3)GlcNAc

4Y1X の概要

関連するPDBエントリー4Y1V 4Y1U 4Y1Y 4Y1Z 4Y20 4Y22 4Y24 4Y26
分子名称Galectin-1, BETA-D-GALACTOSE, methyl 2-(acetylamino)-2-deoxy-6-O-sulfo-beta-D-glucopyranoside, ... (4 entities in total)
機能のキーワードcomplex, galectin-1, sulfated lacnac, galbeta1-4(6oso3)glcnac, sugar binding protein
由来する生物種Homo sapiens (Human)
細胞内の位置Secreted, extracellular space, extracellular matrix  P09382
ポリマー鎖数2
分子量合計34780.84
構造登録者
Lin, H.Y.,Hsieh, T.J.,Lin, C.H. (登録日: 2015-02-09, 公開日: 2016-04-06)
主引用文献
Lin, H.Y.,Hsieh, T.J.,Tu, Z.,Huang, B.S.,Wu, S.C.,Chien, C.T.,Hsu, S.T.,Lin, C.H.
Structural basis of human galectin-1 inhibition with Ki values in the micro- to nanomolar range
To Be Published,
実験手法
X-RAY DIFFRACTION (2.45 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.263800.5%5.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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