4Y0D
Gamma-aminobutyric acid aminotransferase inactivated by (1S,3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115)
Summary for 4Y0D
Entry DOI | 10.2210/pdb4y0d/pdb |
Related | 4Y0H |
Descriptor | 4-aminobutyrate aminotransferase, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, (1S)-4-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]cyclopent-3-ene-1,3-dicarboxylic acid, ... (5 entities in total) |
Functional Keywords | gaba-at, inactivator, transferase |
Biological source | Sus scrofa (Pig) |
Cellular location | Mitochondrion matrix: P80147 |
Total number of polymer chains | 4 |
Total formula weight | 211816.80 |
Authors | Rui, W.,Ruslan, S.,Hyunbeom, L.,Emma, H.D.,Jose, I.J.,Neil, K.,Richard, B.S.,Dali, L. (deposition date: 2015-02-05, release date: 2015-02-25, Last modification date: 2024-02-28) |
Primary citation | Hyunbeom, L.,Emma, H.D.,Rui, W.,Ruslan, S.,Jose, I.J.,Dali, L.,Neil, K.,Richard, B.S. Mechanism of inactivation of gamma-aminobutyric acid aminotransferase by (1S,3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115) J. Am. Chem. Soc., 2015 Cited by PubMed: 25616005DOI: 10.1021/ja512299n PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.19 Å) |
Structure validation
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