4XVY

MycF mycinamicin III 3'-O-methyltransferase in complex with SAH

Summary for 4XVY

• Entry DOI: 10.2210/pdb4xvy/pdb
• Related: 4X7U 4X7V 4X7W 4X7X 4X7Y 4X81 4XVZ
• Descriptor: Mycinamicin III 3''-O-methyltransferase, MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, ... (4 entities in total)
• Functional Keywords: macrolide, methyltransferase, antibiotic, natural product, transferase
• Biological source: Micromonospora griseorubida
• Total number of polymer chains: 2
• Total formula weight: 62450.55

Authors

Akey, D.L.,Smith, J.L. (deposition date: 2015-01-28, release date: 2015-03-04, Last modification date: 2023-09-27)

• Primary citation: Bernard, S.M.,Akey, D.L.,Tripathi, A.,Park, S.R.,Konwerski, J.R.,Anzai, Y.,Li, S.,Kato, F.,Sherman, D.H.,Smith, J.L.; Structural Basis of Substrate Specificity and Regiochemistry in the MycF/TylF Family of Sugar O-Methyltransferases.; Acs Chem.Biol., 10:1340-1351, 2015; PubMed: 25692963; DOI: 10.1021/cb5009348

Experimental method

X-RAY DIFFRACTION (2.42 Å)