4XUJ

Nucleosome core particle containing adducts from treatment with a thiomorpholine-substituted [(eta-6-p-cymene)Ru(3-hydroxy-2-pyridone)Cl] compound

Summary for 4XUJ

• Entry DOI: 10.2210/pdb4xuj/pdb
• Descriptor: Histone H3.2, Histone H4, Histone H2A, ... (10 entities in total)
• Functional Keywords: nucleosome, ruthenium agent, dna-bindig protein-dna complex, dna-binding protein-dna complex, dna-binding protein/dna
• Biological source: Xenopus laevis (African clawed frog); More
• Cellular location: Nucleus: P84233 P62799 Q6AZJ8 P02281
• Total number of polymer chains: 10
• Total formula weight: 199153.51

Authors

Adhireksan, Z.,Davey, C.A. (deposition date: 2015-01-26, release date: 2016-01-27, Last modification date: 2023-11-08)

• Primary citation: Hanif, M.,Meier, S.M.,Adhireksan, Z.,Henke, H.,Martic, S.,Labib, M.,Kandioller, W.,Jakupec, M.A.,Kraatz, H.B.,Davey, C.A.,Keppler, B.K.,Hartinger, C.G.; Contrasting Cytotoxicity and Reactivity of RuII-Arene Complexes of Morpholine vs Thiomorpholine Substituted 3-Hydroxy-2-pyridone Ligands; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.18 Å)