4XUJ

Nucleosome core particle containing adducts from treatment with a thiomorpholine-substituted [(eta-6-p-cymene)Ru(3-hydroxy-2-pyridone)Cl] compound

4XUJ の概要

• エントリーDOI: 10.2210/pdb4xuj/pdb
• 分子名称: Histone H3.2, Histone H4, Histone H2A, ... (10 entities in total)
• 機能のキーワード: nucleosome, ruthenium agent, dna-bindig protein-dna complex, dna-binding protein-dna complex, dna-binding protein/dna
• 由来する生物種: Xenopus laevis (African clawed frog); 詳細
• 細胞内の位置: Nucleus: P84233 P62799 Q6AZJ8 P02281
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 199153.51

構造登録者

Adhireksan, Z.,Davey, C.A. (登録日: 2015-01-26, 公開日: 2016-01-27, 最終更新日: 2023-11-08)

• 主引用文献: Hanif, M.,Meier, S.M.,Adhireksan, Z.,Henke, H.,Martic, S.,Labib, M.,Kandioller, W.,Jakupec, M.A.,Kraatz, H.B.,Davey, C.A.,Keppler, B.K.,Hartinger, C.G.; Contrasting Cytotoxicity and Reactivity of RuII-Arene Complexes of Morpholine vs Thiomorpholine Substituted 3-Hydroxy-2-pyridone Ligands; To Be Published,

実験手法

X-RAY DIFFRACTION (3.18 Å)