4XSE

Complex structure of thymidylate synthase from varicella zoster virus

4XSE の概要

• エントリーDOI: 10.2210/pdb4xse/pdb
• 分子名称: Thymidylate synthase, PHOSPHATE ION (2 entities in total)
• 機能のキーワード: thymidylate synthase, herpesvirus, varicella zoster virus, vzv, viral protein
• 由来する生物種: Varicella-zoster virus (strain Oka vaccine) (HHV-3)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 143455.28

構造登録者

Hew, K. (登録日: 2015-01-22, 公開日: 2015-12-16, 最終更新日: 2024-01-10)

• 主引用文献: Hew, K.,Dahlroth, S.L.,Veerappan, S.,Pan, L.X.,Cornvik, T.,Nordlund, P.; Structure of the Varicella Zoster Virus Thymidylate Synthase Establishes Functional and Structural Similarities as the Human Enzyme and Potentiates Itself as a Target of Brivudine.; Plos One, 10:e0143947-e0143947, 2015; PubMed: 26630264; DOI: 10.1371/journal.pone.0143947

実験手法

X-RAY DIFFRACTION (3.1 Å)