4XRL

Crystal structure at room temperature of Erk2 in complex with an inhibitor

4XRL の概要

• エントリーDOI: 10.2210/pdb4xrl/pdb
• 分子名称: Mitogen-activated protein kinase 1, SULFATE ION, 1H-pyrrolo[2,3-b]pyridine-3-carbonitrile, ... (4 entities in total)
• 機能のキーワード: serine threonine kinase inhibitor, transferase
• 由来する生物種: Rattus norvegicus (Rat)
• 細胞内の位置: Cytoplasm, cytoskeleton, spindle : P63086
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 40319.43

構造登録者

Gelin, M.,Allemand, F.,Labesse, G.,Guichou, J.F. (登録日: 2015-01-21, 公開日: 2016-03-23, 最終更新日: 2016-03-30)

• 主引用文献: Gelin, M.,Delfosse, V.,Allemand, F.,Hoh, F.,Sallaz-Damaz, Y.,Pirocchi, M.,Bourguet, W.,Ferrer, J.L.,Labesse, G.,Guichou, J.F.; Combining 'dry' co-crystallization and in situ diffraction to facilitate ligand screening by X-ray crystallography.; Acta Crystallogr.,Sect.D, 71:1777-1787, 2015; PubMed: 26249358; DOI: 10.1107/S1399004715010342

実験手法

X-RAY DIFFRACTION (2.554 Å)