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4XOC

Crystal structure of the FimH lectin domain from E.coli F18 in complex with heptyl alpha-D-mannopyrannoside

Summary for 4XOC
Entry DOI10.2210/pdb4xoc/pdb
DescriptorFimH protein, heptyl alpha-D-mannopyranoside (3 entities in total)
Functional Keywordstype i pilus, catch-bond, cell adhesion, lectin, upec, bacterial adhesin, uti, mannose, isomerase
Biological sourceEscherichia coli O6:K15:H31
Total number of polymer chains2
Total formula weight34448.34
Authors
Jakob, R.P.,Sauer, M.M.,Navarra, G.,Ernst, B.,Glockshuber, R.,Maier, T. (deposition date: 2015-01-16, release date: 2016-01-27, Last modification date: 2024-01-10)
Primary citationSauer, M.M.,Jakob, R.P.,Eras, J.,Baday, S.,Eris, D.,Navarra, G.,Berneche, S.,Ernst, B.,Maier, T.,Glockshuber, R.
Catch-bond mechanism of the bacterial adhesin FimH.
Nat Commun, 7:10738-10738, 2016
Cited by
PubMed: 26948702
DOI: 10.1038/ncomms10738
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.42 Å)
Structure validation

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