4XO8
Crystal structure of the FimH lectin domain from E.coli K12 in complex with heptyl alpha-D-mannopyrannoside
Summary for 4XO8
| Entry DOI | 10.2210/pdb4xo8/pdb |
| Descriptor | Protein FimH, heptyl alpha-D-mannopyranoside (3 entities in total) |
| Functional Keywords | type i pilus, cell adhesion, lectin, upec, bacterial adhesin, mannose, uti, catch bond |
| Biological source | Escherichia coli K-12 |
| Cellular location | Fimbrium: P08191 |
| Total number of polymer chains | 2 |
| Total formula weight | 34390.34 |
| Authors | Jakob, R.P.,Eras, J.,Navarra, G.,Ernst, B.,Glockshuber, R.,Maier, T. (deposition date: 2015-01-16, release date: 2016-01-27, Last modification date: 2024-01-10) |
| Primary citation | Sauer, M.M.,Jakob, R.P.,Eras, J.,Baday, S.,Eris, D.,Navarra, G.,Berneche, S.,Ernst, B.,Maier, T.,Glockshuber, R. Catch-bond mechanism of the bacterial adhesin FimH. Nat Commun, 7:10738-10738, 2016 Cited by PubMed: 26948702DOI: 10.1038/ncomms10738 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.698 Å) |
Structure validation
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