4XNV

The human P2Y1 receptor in complex with BPTU

Summary for 4XNV

• Entry DOI: 10.2210/pdb4xnv/pdb
• Related: 4XNW
• Descriptor: P2Y purinoceptor 1, Rubredoxin, P2Y purinoceptor 1, 1-[2-(2-tert-butylphenoxy)pyridin-3-yl]-3-[4-(trifluoromethoxy)phenyl]urea, CHOLESTEROL, ... (8 entities in total)
• Functional Keywords: human p2y1 receptor, g protein coupled receptor, platelet activation, membrane protein, inhibitor complex, transport protein-inhibitor complex, psi-biology, structural genomics, gpcr network, gpcr, transport protein/inhibitor
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 1
• Total formula weight: 52916.56

Authors

Zhang, D.,Gao, Z.,Jacobson, K.,Han, G.W.,Stevens, R.,Zhao, Q.,Wu, B.,GPCR Network (GPCR) (deposition date: 2015-01-16, release date: 2015-04-01, Last modification date: 2020-02-05)

• Primary citation: Zhang, D.,Gao, Z.G.,Zhang, K.,Kiselev, E.,Crane, S.,Wang, J.,Paoletta, S.,Yi, C.,Ma, L.,Zhang, W.,Han, G.W.,Liu, H.,Cherezov, V.,Katritch, V.,Jiang, H.,Stevens, R.C.,Jacobson, K.A.,Zhao, Q.,Wu, B.; Two disparate ligand-binding sites in the human P2Y1 receptor; Nature, 520:317-321, 2015; PubMed: 25822790; DOI: 10.1038/nature14287

Experimental method

X-RAY DIFFRACTION (2.2 Å)