4XNU
X-ray structure of Drosophila dopamine transporter in complex with nisoxetine
Summary for 4XNU
| Entry DOI | 10.2210/pdb4xnu/pdb |
| Related | 4M48 4XNX |
| Descriptor | Integral membrane protein-dopamine transporter, antibody fragment light chain, antibody fragment heavy chain, ... (8 entities in total) |
| Functional Keywords | integral membrane protein, all-alpha helical antidepressant complex, transport protein-inhibitor complex, transport protein/inhibitor |
| Biological source | Drosophila melanogaster More |
| Total number of polymer chains | 3 |
| Total formula weight | 109651.42 |
| Authors | Aravind, P.,Wang, K.,Gouaux, E. (deposition date: 2015-01-16, release date: 2015-05-13, Last modification date: 2023-09-27) |
| Primary citation | Penmatsa, A.,Wang, K.H.,Gouaux, E. X-ray structures of Drosophila dopamine transporter in complex with nisoxetine and reboxetine. Nat.Struct.Mol.Biol., 22:506-508, 2015 Cited by PubMed: 25961798DOI: 10.1038/nsmb.3029 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.98 Å) |
Structure validation
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