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4XNU

X-ray structure of Drosophila dopamine transporter in complex with nisoxetine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Integral membrane protein-dopamine transporterpolymer53259684.11Pfam (PF00209)
UniProt (by SIFTS) (Q7K4Y6)
Drosophila melanogaster
2B
(L)
antibody fragment light chainpolymer21423306.61Mus musculus
3C
(H)
antibody fragment heavy chainpolymer24025921.31Mus musculus
4D, E
(A)
SODIUM IONnon-polymer23.02Chemie (NA)
5F
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
6G
(A)
CHOLESTEROLnon-polymer386.71Chemie (CLR)
7H
(A)
nisoxetinenon-polymer271.41Chemie (41U)
8I
(A)
waterwater18.08Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight108912.0
Non-Polymers*Number of molecules5
Total formula weight739.4
All*Total formula weight109651.4
*Water molecules are not included.

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PDB entries from 2025-06-11

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