4XMP

Crystal structure of broadly and potently neutralizing antibody VRC08 in complex with HIV-1 clade A strain Q842.d12 gp120

4XMP の概要

• エントリーDOI: 10.2210/pdb4xmp/pdb
• 関連するPDBエントリー: 4XNY 4XNZ
• 分子名称: Envelope glycoprotein gp160,Envelope glycoprotein gp160,Envelope glycoprotein gp160, HEAVY CHAIN OF ANTIBODY VRC08, LIGHT CHAIN OF ANTIBODY VRC08, ... (6 entities in total)
• 機能のキーワード: antibody, hiv-1, immune system
• 由来する生物種: Human immunodeficiency virus 1; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 90549.73

構造登録者

Zhou, T.,Srivatsan, S.,Kwong, P.D. (登録日: 2015-01-15, 公開日: 2015-04-29, 最終更新日: 2023-09-27)

• 主引用文献: Wu, X.,Zhang, Z.,Schramm, C.A.,Joyce, M.G.,Do Kwon, Y.,Zhou, T.,Sheng, Z.,Zhang, B.,O'Dell, S.,McKee, K.,Georgiev, I.S.,Chuang, G.Y.,Longo, N.S.,Lynch, R.M.,Saunders, K.O.,Soto, C.,Srivatsan, S.,Yang, Y.,Bailer, R.T.,Louder, M.K.,Mullikin, J.C.,Connors, M.,Kwong, P.D.,Mascola, J.R.,Shapiro, L.; Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection.; Cell, 161:470-485, 2015; PubMed: 25865483; DOI: 10.1016/j.cell.2015.03.004

実験手法

X-RAY DIFFRACTION (1.7831 Å)