4XJE
CRYSTAL STRUCTURE OF ANT(2") IN COMPLEX WITH AMP AND TOBRAMYCIN
Summary for 4XJE
Entry DOI | 10.2210/pdb4xje/pdb |
Related | 1KNY 3ISD 5CFS 5CFT 5CFU |
Descriptor | AadB, ADENOSINE MONOPHOSPHATE, TOBRAMYCIN, ... (5 entities in total) |
Functional Keywords | antibiotic resistance, nucleotidyltransferase, tobramycin, rossmann fold, transferase-antibiotic complex, transferase/antibiotic |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 1 |
Total formula weight | 21871.35 |
Authors | Rodionov, D.,Bassenden, A.V.,Berghuis, A.M. (deposition date: 2015-01-08, release date: 2016-01-20, Last modification date: 2024-02-28) |
Primary citation | Bassenden, A.V.,Park, J.,Rodionov, D.,Berghuis, A.M. Revisiting the Catalytic Cycle and Kinetic Mechanism of AminoglycosideO-Nucleotidyltransferase(2′′): A Structural and Kinetic Study. Acs Chem.Biol., 2020 Cited by PubMed: 32100995DOI: 10.1021/acschembio.9b00904 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.88 Å) |
Structure validation
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