4XI5

gHgL of varicella-zoster virus in complex with human neutralizing antibodies

4XI5 の概要

• エントリーDOI: 10.2210/pdb4xi5/pdb
• 関連するPDBエントリー: 4XHJ
• 分子名称: Envelope glycoprotein H, Envelope glycoprotein L, Fab-94 light chain, ... (6 entities in total)
• 機能のキーワード: complex, neutralization epitope, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Human herpesvirus 3 strain Oka vaccine (HHV-3); 詳細
• 細胞内の位置: Virion membrane ; Single-pass type I membrane protein : Q775J3; Virion membrane ; Peripheral membrane protein ; Extracellular side : Q9J3N1
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 162744.49

構造登録者

Xing, Y. (登録日: 2015-01-06, 公開日: 2015-05-13, 最終更新日: 2023-09-27)

• 主引用文献: Xing, Y.,Oliver, S.L.,Nguyen, T.,Ciferri, C.,Nandi, A.,Hickman, J.,Giovani, C.,Yang, E.,Palladino, G.,Grose, C.,Uematsu, Y.,Lilja, A.E.,Arvin, A.M.,Carfi, A.; A site of varicella-zoster virus vulnerability identified by structural studies of neutralizing antibodies bound to the glycoprotein complex gHgL.; Proc.Natl.Acad.Sci.USA, 112:6056-6061, 2015; PubMed: 25918416; DOI: 10.1073/pnas.1501176112

実験手法

X-RAY DIFFRACTION (3.9 Å)