4XFS

Structure of IL-18 SER Mutant I

Summary for 4XFS

DescriptorInterleukin-18, DIMETHYL SULFOXIDE, GLYCEROL, ... (4 entities in total)
Functional Keywordsinterleukin-18, il-18, cytokine, immune defense, surface entropy reduction
Biological sourceHomo sapiens (Human)
Cellular locationSecreted Q14116
Total number of polymer chains2
Total molecular weight36505.6
Authors
Krumm, B.E.,Meng, X.,Xiang, Y.,Deng, J. (deposition date: 2014-12-28, release date: 2015-06-10, Last modification date: 2017-09-20)
Primary citation
Krumm, B.,Meng, X.,Xiang, Y.,Deng, J.
Crystallization of interleukin-18 for structure-based inhibitor design.
Acta Crystallogr.,Sect.F, 71:710-717, 2015
PubMed: 26057800 (PDB entries with the same primary citation)
DOI: 10.1107/S2053230X15006871
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.91 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.240800.7%1.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution