4XCE

Crystal structure of human 4E10 Fab crystalized in the presence of Phosphatidylcholine (06:0 PC); C2 space group

Summary for 4XCE

• Entry DOI: 10.2210/pdb4xce/pdb
• Related: 4XAW 4XBE 4XBG 4XBP 4XC1 4XC3 4XCC 4XCF 4XCN 4XCY
• Descriptor: 4E10 Fab light chain, 4E10 Fab heavy chain (3 entities in total)
• Functional Keywords: 4e10 fab anti hiv-1 gp41, phosphatidylcholine, membrane lipid, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 6
• Total formula weight: 142728.30

Authors

Irimia, A.,Stanfield, R.L.,Wilson, I.A. (deposition date: 2014-12-17, release date: 2016-02-03, Last modification date: 2023-09-27)

• Primary citation: Irimia, A.,Sarkar, A.,Stanfield, R.L.,Wilson, I.A.; Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.; Immunity, 44:21-31, 2016; PubMed: 26777395; DOI: 10.1016/j.immuni.2015.12.001

Experimental method

X-RAY DIFFRACTION (2.93 Å)